PL-3.2 Hyperthyroidism

Magali Bidal-St-Aubin, Canada

Endocrinologist
Lakeshore Diabetes and Endocrinology

Questions Submitted

  • How do you treat thyroid storm?
    Response: We use iodine, IV steroids, IV methimazole, high doses of beta blockers.

  • Do you recommend prenatal screening with TSH for all women even without hx of thyroid disease?
    Response: Yes, can help especially in women who are having difficulties conceiving.

  • For RAIU scan, are there any implications on patients / restrictions, once they take the radioactive iodine - i.e. limiting contact with family members?
    Response: Not for the scan. The dose is extremely small, and it is a tracer (123 iodine) rather than a treatment (131 iodine). No restrictions needed.

  • In patients with recurrent thyroiditis, do they have increased risk of developing another cause of hyperthyroidism?
    Response: No, they will just get recurrent subacute thyroiditis.

  • When someone gets ectopic heartbeats during a viral resp infection, could this be transient thyroiditis?
    Response: Thyroid dysregulation takes 2-4 weeks to present itself post viral infection, therefore unlikely that symptoms during the viral infection would be caused by hyperthyroidism.

  • Every Graves d pt needs to see an opthalmologist?
    Response: No, only if they have symptoms (most patients with Graves will not have Graves orbitopathy).

  • Why is PTU not first line treatment for Grave's?
    Response: It has more adverse effect risk (agranulocytosis or hepatic dysfunction) than methimazole. However in pregnancy first trimester it has less risk of fetal malformation than methimazole.

  • Sub-clinical hypothyroid question: Pt could not get appt w her GP, so presented to me with TSH 16, normal T4. I found her ferritin was low, pt was not taking her Rx iron pills. So I altered her po iron to different form & referred to thryoid Dr on CRDS. However the form as a pre-requisite requests a TSH level and a thyroid scan - what is being checked for in the scan?
    Response: Not sure why they would ask for a scan. Not helpful in hypothyroidism. But with a TSH above 10 you can start synthroid (even if normal T4).

Objectives

  1. To describe the most common causes of hyperthyroidism in the outpatient setting
  2. To determine when a referral is indicated
  3. To establish what tests and preliminary treatments can be given prior to referring to an endocrinologist

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